Hi Are you talking about experiencing acute chest syndrome (a very scary complication that sometimes follows an acute pain crisis affecting blood flow to the lungs). Some of our community members have worked with their medical team for hydroxyurea or similar medications. Here's one person's experience with that: https://sickle-cell.com/living/hydroxyurea-experience. Please let us know how you are doing. I wish you all the best. Kathy (Team member)