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...Sickle cell disease (SCD) is a lifelong illness caused by an abnormal protein in red blood cells. Red blood cells become rigid and sickle-shaped. Sickle cells can block blood flow...

...A history of discriminatory policies in the United States has led to racial inequalities in all levels of society, including education, healthcare, and wealth. Because people in the United States...

...About 1 in 4 young children with sickle cell disease (SCD) experience a complication called splenic sequestration crisis. This happens when the spleen enlarges because of trapped red blood cells...

...Finding a spouse or partner can be especially stressful for people with SCD. Different aspects of the disease make dating more complicated. However, people with SCD are not inferior partners...

...Sickle cell disease (SCD) affects about 100,000 people in the United States. Most people who have SCD in the United States are Black. It is also common in Hispanic Americans...

...Sickle cell disease (SCD) can cause long-term complications. Most people experience acute and chronic injuries to different organs. This can increase healthcare costs, reduce quality of life, and a shorten...

...Sickle cell disease (SCD) is a disorder due to the inheritance of an abnormal hemoglobin gene. This gene is not on the sex chromosome. This means there is no sex-related...

...Sickle cell disease (SCD) is a genetic disorder that affects red blood cells. A major challenge in treating people with SCD is a lack of information. Many adolescents transitioning to...

...Sickle cell disease (SCD) is a group of genetic red blood cell disorders. Normally, red blood cells are round and flexible. But people with SCD have rigid red blood cells...

...Lifestyle changes will not cure sickle cell disease (SCD). However, when they are combined with other treatments, lifestyle changes may reduce the frequency and severity of acute pain crises. It...

...When acute pain cannot be controlled at home, stronger pain medicines in an emergency room (ER) are needed. However, seeking help at the ER is often a stressful experience for...

...Sickle cell crisis is the most common complication of sickle cell disease (SCD). Acute episodes of pain can occur anywhere in the body and may lead people to seek hospital...

...People who have 1 gene for sickle hemoglobin and 1 gene for normal hemoglobin have sickle cell trait (SCT). They usually do not show symptoms of sickle cell disease, but...

...Pulmonary (lung) disease is common and a leading cause of death for people with sickle cell disease (SCD). Pulmonary hypertension and acute chest syndrome are some of the most common...

...Sickle cell disease (SCD) researchers expect powerful new treatments to come in the next few years. About 30 drugs are currently in late-stage clinical trials to treat SCD. These drugs...

...Children under 5 years old who have sickle cell disease (SCD) have a higher risk of severe infections. This is because SCD can damage the spleen. The spleen is an...

...Most people with sickle cell disease (SCD) experience an acute pain episode in their lifetime. The first episode can occur as early as 6 months old. Pain episodes occur with...

...Acute pain episodes are the most common cause of hospitalization for people with sickle cell disease (SCD). However, most episodes are managed at home. Plan with your doctor how you...

...Sickle cell disease (SCD) is a lifelong inherited condition that affects red blood cells. Normally, red blood cells are round and flexible, so they can pass easily through blood vessels....